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Answer: the mistreatment of Native Americans on their land and the expansion of America westward were the main contributing factors.

Explanation:
Manifest Destiny
Explanation: The idea of Manifest Destiny was centered around expanding westward and that America was destined by god to take over the North American Continent. As America expanded West, they would have to interfere with the Natives and American Indians. This naturally led to wars between the two. Hope this helps

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