santimuper8401 santimuper8401
  • 03-03-2020
  • Chemistry
contestada

Whch compounds is most reactive toward nucleophilic acyl substitution?

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osagieosazeme72
osagieosazeme72 osagieosazeme72
  • 08-03-2020

Answer:

There are five main types of acyl derivatives. Acid halides are the most reactive towards nucleophiles, followed by anhydrides, esters, and amides. Carboxylate ions are essentially unreactive towards nucleophilic substitution, since they possess no leaving group

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